Calculate MELD Score

Laboratory Values

Understanding the MELD Score Calculator

The Model for End-Stage Liver Disease (MELD) Score is a reliable tool for assessing the severity of chronic liver disease and predicting mortality risk. This scoring system is crucial for prioritizing patients for liver transplantation.

Score Interpretation

MELD scores range from 6 to 40, with higher scores indicating more severe disease and greater urgency for liver transplantation.

Critical Values

Scores above 30 indicate high priority for transplantation with significant mortality risk.

Clinical Applications of MELD Score

Transplant Prioritization

Primary tool for liver allocation in organ transplantation systems worldwide

Mortality Prediction

Accurate assessment of 3-month mortality risk in patients with end-stage liver disease

Treatment Planning

Guides clinical decision-making and timing of interventions

Latest Research on MELD Score

MELD-Na Evolution

The incorporation of serum sodium has improved the predictive accuracy of the MELD score, particularly in patients with ascites and hyponatremia.

Validation Studies

Recent studies confirm MELD's reliability across different patient populations and its superiority over older scoring systems.

Dynamic Assessment

Changes in MELD score over time provide valuable prognostic information and help optimize transplant timing.

Components of MELD Score

Serum Bilirubin

Measures liver's ability to excrete bile and indicates severity of liver dysfunction

INR (International Normalized Ratio)

Reflects liver's synthetic function and coagulation status

Serum Creatinine

Indicates renal function, often affected in advanced liver disease

Serum Sodium

Added in MELD-Na to account for the impact of hyponatremia

Best Practices for MELD Score Assessment

Regular Monitoring

Assess MELD score every 3 months or more frequently in severe cases

Laboratory Accuracy

Use standardized laboratory methods and ensure result consistency

Documentation

Maintain detailed records of score progression and clinical correlation

The MELD Score calculator is designed for healthcare professionals. Results should be interpreted alongside clinical judgment and other relevant patient data. This tool should not be used as the sole basis for clinical decisions.